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Best American Restaurant in Anderson

Gather Together Where Flavor, Friendship, And Warmth Meet
Welcome to Doolittle’s

Welcome to Doolittle’s

The Doolittle Family invites you to rediscover the charm of beautiful Downtown Anderson! At Doolittle’s, every dish is crafted fresh and in-house, blending local flavors with coastal inspirations. John and Shandra have created a warm, welcoming atmosphere where great food and genuine hospitality come together. Whether you’re sharing a meal with family, catching up with friends, or making new ones, Doolittle’s is the perfect place to gather, relax, and enjoy. 📍 112 N Main St, Anderson.
Where Every Bite Tells A Story Of Freshness & Care

Where Every Bite Tells A Story Of Freshness & Care

At Doolittle’s, taste is more than just flavor it’s an experience. Each dish is crafted with the finest local ingredients and a touch of coastal inspiration, made fresh and in-house every day. From the first bite to the last, you’ll discover a balance of richness, freshness, and authenticity that makes every meal unforgettable. It’s the kind of flavor that brings people together, creating moments you’ll want to savor again and again.

Order From Our Website

Craving your Doolittle’s favorites? Skip the wait and enjoy the same fresh, in-house flavors from the comfort of your home. With just a few clicks, you can place your order online and have it ready for pickup or delivered straight to your door. Fast, simple, and delicious because great food should always be within reach.
Catering Made Simple, Flavor Made Memorable

Catering Made Simple, Flavor Made Memorable

Bring the warmth, flavor, and hospitality of Doolittle’s to your next event. Whether it’s a family gathering, corporate luncheon, or special celebration, our fresh, in-house cuisine and friendly service will make it unforgettable. Let us take care of the food so you can focus on the moments that matter most.
Reserve Your Table Today

Reserve Your Table Today

Enjoy the perfect dining experience at Doolittle’s by reserving your table in advance. Whether it’s a cozy dinner for two, a family gathering, or a night out with friends, we’ll make sure your spot is ready with the warm hospitality and fresh flavors you love. Secure your place today and let us take care of the rest.
Celebrate Your Special Occasion With Us

Celebrate Your Special Occasion With Us

Turn life’s milestones into unforgettable memories at Doolittle’s. Whether it’s a birthday, anniversary, or family gathering, our warm atmosphere, fresh cuisine, and genuine hospitality create the perfect backdrop for your celebration. Let us make your special day feel even more extraordinary.

Wow! Love this place. Food was on point! BBQ pork over Mac was killer. Green beans were delicious. Definitely will be back!

David E.

We are on vacation at nearby Lake Hartwell. My husband said the Reuben was one of the best he had had. I had the fish & chips which were good. Our waitress was excellent!

Karen B.

This was the 2nd time we've eaten here, and it didn't disappoint us. Wonderful food, service, and people. Thank you

Stephen H.

Featuring

Catering

Dine In

Delivery

Take Out

Reservation

Happy Hours

Great Cocktails

Live Music

Doolittle's Rewards

Join our rewards program, earn points every time you order online and redeem your points for free food!

Frequently Asked Questions

What are you known for?

We’re known for American comfort food in Anderson, featuring hearty burgers, sandwiches, Chesapeake crab cakes, and shrimp and grits.

  • American Food: American comfort food spans burgers, pulled pork sandwiches, hand-breaded chicken tenders, and Southern favorites like shrimp and grits. Examples include Carolina burger, Pulled pork sandwich, Hand breaded chicken tenders, Shrimp and Grits - Dinner, and Mac and cheese.
  • Seafood: Seafood ranges from peel-and-eat shrimp, calamari, and mussels to Chesapeake crab cakes, fish tacos, and shrimp with grits. Examples include Peel and eat shrimp, Fried calamari, Wild blue mussels, Chesapeake crab cake - dinner, Fish tacos, and Shrimp and Grits - Dinner.
  • Sandwiches: Sandwiches offer pulled pork, grilled chicken, cheesesteak, crab cake melts, and comforting grilled cheese alongside a veggie wrap. Examples include Pulled pork sandwich, Grilled chicken sandwich, Cheesesteak sandwich, Crabcake melt sandwich, Three Cheese Grill Sandwich, and Veggie Wrap.
  • Chicken: Chicken comes in hand-breaded tenders, Buffalo thighs, grilled sandwiches, Alfredo pasta, and quesadillas. Examples include Hand breaded chicken tenders, Buffalo Thighs, Grilled chicken sandwich, Chicken alfredo pasta, and Chicken quesadilla.
  • Crab: Crab features in Chesapeake-style cakes, Maryland cream soup, pimento dip, sandwich melts, and Alfredo pasta with shrimp. Examples include Chesapeake crab cake - dinner, Maryland cream of crab soup, Crab and pimento dip, Crabcake melt sandwich, and Crab and shrimp alfredo pasta.

Additionally, explore Burgers, Salads, Soups, Drinks, Pasta, and Wraps.

What meals do you serve?

We serve Brunch

Do you offer delivery or takeout?

Yes, we offer Delivery and Takeout

Where are you located?

We are located in Anderson, SC at 112 N Main St

What areas do you serve?

Our location

Map showing the location of Doolittle's on 112 N Main St in Anderson
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